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Updated: Jul 14, 2026

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Nursing Neonatal Nurse Practitioner Sample Questions:

1. The NP is assessing an infant with renal disease. Over the past 4 hours, he has had 100 mL of urine output. He weighs 6 lbs,or 2.73 kg. The initial interpretation of this would be

A) normal urine output for weight of the infant
B) severe oliguria
C) severe polyuria


2. A neonate suffered perinatal asphyxia and developed moderate hypoxic ischemic encephalopathy (HIE) with neurological dysfunction. The treatment that is LEAST likely to be utilized to treat this condition is

A) fluid resuscitation
B) therapeutic hypothermia
C) phenobarbital


3. A newborn in the NICU has been receiving gentamicin and ampicillin for the treatment of gram negative sepsis. He is on a fairly high dose of gentamicin and has been for the past 3 days. In addition to the risk of developing renal impairment from the medication, he is also at risk for

A) hearing loss
B) permanent discoloration of his teeth later in life
C) cataract development


4. A newborn has an NG tube in place due to an intestinal obstruction. In order to prevent aspiration of saliva, it is very important to

A) the aspirate should drain into a drainage bag without any manual aspiration
B) the aspirate should drain into a drainage bag and the stomach contents should be aspirated
C) perform continuous oral suction


5. What is a patent ductus arteriosus?

A) A widening of the mitral valve resulting in mitral regurgitation
B) An opening in the septal wall between the left and right ventricles
C) An opening between the pulmonary and aortic arteries


Solutions:

Question # 1
Answer: C
Question # 2
Answer: A
Question # 3
Answer: A
Question # 4
Answer: B
Question # 5
Answer: C

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